LH1307
T36047
CAS Number2375720-38-8
Product group Chemicals
Molecular Weight915.108
Overview
- SupplierTargetMol Chemicals
- Product NameLH1307
- Delivery Days Customer1001
- CAS Number2375720-38-8
- Category SupplierChemical
- Chemical NameLH1307
- Molecular FormulaC54H58N8O6
- Molecular Weight915.108
- Scientific DescriptionLH1307 is an inhibitor of the interaction between programmed cell death 1 (PD-1) and its ligand PD-L1 that has an IC50 value of 3 nM in a homologous time-resolved fluorescence (HTRF) assay.1 It increases the activation of Jurkat cells expressing PD-1 in co-culture with U2OS or CHO cells expressing PD-L1 (EC50s = 79 and 763 nM, respectively, in reporter assays).
- Shelf life instruction3 years
- SMILESCC(=O)NCCNCc1cc(C)c(OCc2cccc(c2C)-c2cccc(COc3cc(OCc4cncc(c4)C#N)c(CNCCNC(C)=O)cc3C)c2C)cc1OCc1cncc(c1)C#N
- Storage Instruction-20°
- UNSPSC12352200