Mercodia Lispro NL-ELISA

Mercodia is launching a new ELISA kit for the insulin analog Lispro. This easy-to-use, high quality PK assay meets the pharmaceutical industry requirements for multiple phases of drug development.

Insulin lispro is a rapid-acting insulin analog that was first introduced in 1996 to treat people with diabetes. In research projects, as well as pharmacological projects it is important to be able to differentiate the insulin analog lispro from endogenous insulin and other insulin analogs. To this end, Mercodia has developed a highly specific antibody with these properties.

This novel Lispro ELISA is both sensitive and specific for the determination of insulin lispro. With pre-diluted calibrators in serum matrix at six levels, as evidenced by the robust assay performance characteristics, this method meets the requirements of EMA and FDA validation. The assay uses chemiluminescence detection and displays no interference from auto-insulin antibodies, and therefore no pre-treatment or dilution of samples is necessary.

The new assay is validated for use on human as well as porcine plasma and serum. Porcine is an important animal model for studies on diabetes and its treatment, the assay is designed not to cross react with endogenous insulin or proinsulin. This makes it possible to use on healthy pigs, releasing researchers of the economical and time-consuming burden of having to use diabetic pigs in their projects.



Description

Mercodia Lispro NL-ELISA is designed to be an excellent assay for pharma use. It provides a chemiluminescent method for the quantitative determination of insulin lispro.

Advantages

  • Optimized for pharma use, including six calibrators, two anchor points and controls in serum matrix. Validation data available.
  • No cross-reactivity to endogenous insulin or other insulin analogs e.g. glargine.
  • No interference from insulin auto-antibodies
  • Fully validated for use with human and pig samples
  • Broad measuring range
  • No pre-treatment or dilution of samples
  • Low sample volume - 10 μL
  • Results in 2h 15min
Cat. No.Description
Measurement Range
Amount
10-1291-01
Lispro NL-ELISA
1 - 500 mU/L
1 x 96 wells

For more information, download the poster: Validation of a novel insulin lispro ELISA



Related to:
Brands: Mercodia
Product groups: Assays