MMP13-IN-2 [935759-55-0]

MedChem Express

MMP13-IN-2 [935759-55-0]

10

935759-55-0

Research Use Only

98.19%

C24H19FN6O4S

506.51

MMP13-IN-2 is a potent, selective and orally active MMP-13 inhibitor. MMP13-IN-2 exhibits excellent potency for MMP-13 (IC50=0.036 nM) and selectivities (greater than 1,500-fold) over MMP-1, 3, 7, 8, 9, 14, and TACE. MMP13-IN-2 has the ability to block the release of collagen from cartilage in vitro. MMP13-IN-2 has the potential for collagenase related disease research.

O=C(C(NC1=C2C(C3=CC=CC(F)=C3)=CS1)=NC2=O)NCC4=CC=CC(OCCOC5=NC=NN5)=C4

2°C to 8°C,-20°C,-80°C

12352200