Recombinant Human Cathepsin B/CTSB Protein(C-6His)

General

Product specifications for - Recombinant Human Cathepsin B/CTSB Protein(C-6His)

Overview:
Product group:	Molecular Biology
Category:	Restriction / modifying enzymes
Subcategory:	Proteases
Source:	Human

Properties:
Purity:	>95% as determined by reducing SDS-PAGE.
Assay Test Principle:	Measured by its ability to cleave the fluorogenic peptide substrate Z-LR-AMC Specific Activity is greater than 3000 pmol/min/ug
	Research Use Only
UNSPSC:	12352204
Form supplied:	Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
Storage instructions:	Store at < -20°C, stable for 6 months after receipt. Please minimize freeze-thaw cycles

Scientific information:
Scientific info:	Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes
Swiss prot ID:	P07858

Scientific information:

Scientific info:

Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes

Swiss prot ID:

P07858

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Product specifications for - Recombinant Human Cathepsin B/CTSB Protein(C-6His)