Neuropilin-1 is a host factor for SARS-CoV-2 infection

Neuropilin-1 (NRP1) is abundantly expressed in the respiratory and olfactory epithelium, with highest expression in endothelial cells and in the epithelial cells facing the nasal cavity. Neuropathological analysis of human COVID-19 autopsies revealed SARS-CoV-2 infected NRP1-positive cells in the olfactory epithelium and bulb.

NRP1 can reliably be measured by ELISA in human serum, plasma and urine samples with a fully validated assay. Only 10 µl of sample volume is required!

Daly JL, Simonetti B, Antón-Plágaro C, et al. Neuropilin-1 Is a Host Factor for SARS-CoV-2 Infection. Cell Biology; 2020.

Biomedica offers the Neuropilin-1 ELISA, Catno: BI-20409, to detect Neuropilin-1 in human as well as non-human samples