PD-1/PD-L1-IN-13
HY-145239
Overview
- SupplierMedChem Express
- Product NamePD-1/PD-L1-IN-13
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity99.52%
- Molecular FormulaC36H34ClF2N3O9
- Molecular Weight726.12
- Scientific DescriptionPD-1/PD-L1-IN-13 (Compound 43) is a potent immune checkpoint PD-1/PD-L1 inhibitor with an IC50 value of 10.2 nM. PD-1/PD-L1-IN-13 promots CD8+ T cell activation and delays the tumor growth in the Hepa1-6 syngeneic mouse model.
- SMILESCC1=C(C=CC=C1C(F)(F)OC2=C(Cl)C=C(CN[C@@H]3C(O)O[C@H](CO)[C@@H](O)[C@@H]3O)C(OCC4=CC(C#N)=NC=C4)=C2)C5=CC=C(OCCO6)C6=C5
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200