PD-1/PD-L1-IN-29
HY-152240
Molecular Weight460.48
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NamePD-1/PD-L1-IN-29
- Delivery Days Customer10
- CertificationResearch Use Only
- Molecular FormulaC26H24N2O6
- Molecular Weight460.48
- Scientific DescriptionPD-1/PD-L1-IN-29 (S4-1) is a potent PD-1/PD-L1 inhibitor with an IC50 value of 6.1 nM. PD-1/PD-L1-IN-29 binds PD-L1 and disrupts PD-1/PD-L1 interactions, induces PD-L1 dimerization and internalization, improves its localization to the endoplasmic reticulum, and promotes PD-L1 entry into the endoplasmic reticulum. PD-1/PD-L1-IN-29 has anticancer activity.
- SMILESOC[C@H](NCC1=CC2=C(C=C1OC)C(N(C2=O)C3=C(C(C4=CC=CC=C4)=CC=C3)C)=O)C(O)=O
- Storage InstructionSee Manual
- UNSPSC12352200