PD-1/PD-L1-IN-9 hydrochloride

MedChem Express

PD-1/PD-L1-IN-9 hydrochloride

10

Research Use Only

99.26%

C22H25ClN2O2

384.9

PD-1/PD-L1-IN-9 hydrochloride is a potent and orally active inhibitor of PD-1/PD-L1 interaction, with an IC50 of 3.8 nM. PD-1/PD-L1-IN-9 hydrochloride can enhance the killing activity of tumor cells by immune cells. PD-1/PD-L1-IN-9 hydrochloride also exhibits significant in vivo antitumor activity in a CT26 mouse model.

CC1=C(C=CC=C1C2=CC=CC=C2)C3=NC(OC)=C(C=C3)CNCCO.[H]Cl

2°C to 8°C,-20°C,-80°C

12352200