Shopping Cart
Your shopping cart is empty
Login
Register
Forgot Password?
Home
Products
Suppliers
News
Promotions
Helpdesk
About Bio-Connect Diagnostics
Our Divisions
Our Team
Quality and Environmental Management
Meet us at
Contact
COVID-19 Tests & Assay kits
CE-marked
ELISA Kits
Luminex®
Next Generation Sequencing
Polymerase Chain Reaction
Radioactive Products
Rapid Diagnostic Tests
Join us
Description
Catalog number
CAS No.
Clone ID
Order information
Order online, fax your order to +31 (0)26 326 4461 or e-mail your order to
orders(at)bio-connect.nl
.
Need another amount?
Contact us
to find out the possibilities.
Can't find what you are looking for?
Bio-Connect Services specialises in assisting you in finding all the products you need for your research. Check out our video to see how it works or go to
www.bio-connectservices.com/how-it-works
.
News
SARS-CoV-2 S2 N defined peptide pool
Reading up on Science with our partner Mercodia
COVID-19 EXBIO Dry Reagent kits
A novel in vitro screening tool of anti-lipidemic drugs
Endostatin is an independent risk factor of graft loss after kidney transplant
Titin N-Fragment Assay Kit
SARS-CoV-2 related products by Cusabio
Notification for TCRB Gene Clonality Assay Kits
Human CD134/OX40 Assay Kit
HLA-G Antibodies
Vorige
Volgende
Active Interleukin 10 (IL10)
Catalog number:
APA056HU61_50ug
Brand:
Cloud-Clone Corp.
Packing:
50 ug
Price:
On Request
Expected delivery time:
7 days
Quantity:
Spin Up
Spin Down
General
Pictures
Interleukin 10 (IL-10), also known ...
Interleukin 10 (IL-10), also known as human cytokine synthesis inhibitory factor (CSIF), is an anti-inflammatory cytokine. IL-10 was initially reported to suppress cytokine secretion, antigen presentation and CD4 T cell activation. Further investigation has shown that IL-10 predominantly inhibits lipopolysaccharide (LPS) mediated induction of the pro-inflammatory cytokines TNFα, IL-1β, IL-12, and IFNγ made by cells such as macrophages and Th1 T cells. Therefore, THP1 cells were cultured in 24 well plates at a concentration of 106 cells/ml and activated by LPS (1ug/mL) in the absence or presence of IL-10 (5ng/mL, 10ng/mL) for 24h and production of IL-1β was determined in the supernatants by cytokine specific ELISA.
Activation of THP1 cells with LPS (1ug/mL) resulted in high levels of production of IL-1β and strong inhibitory effects of IL-10 (5ng/mL, 10ng/mL) were observed on the production of IL-1β as shown in Table 1.
Product specifications for - Active Interleukin 10 (IL10)
Overview:
Product group:
Proteins / Signaling Molecule
Category:
Chemokines / cytokines
Application:
Other Application
Application note:
Cell culture, Activity Assays, In vivo assays.
Modification:
N-terminal His Tag
Properties:
Purity:
> 97%
Molecular weight:
18kDa
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352202
Scientific information:
Scientific info:
Eukaryotic expression
Swiss prot ID:
P22301
Additional information:
Synonyms:
APA056HU61
