RCC1 (RanGEF), Regulator of Chromosome Condensation, Ran Guanine Exchange Factor, human, recombinant, E. coli

Jena Bioscience

RCC1 (RanGEF), Regulator of Chromosome Condensation, Ran Guanine Exchange Factor, human, recombinant, E. coli

5

Research Use Only

>90%

RCC1 (Regulator of Chromosome Condensation, a beta propeller chromatin-bound protein) catalyzes guanine nucleotide exchange of the Ras-related nuclear protein Ran. RCC1 is the guanine nucleotide exchange factor (GEF) for Ran which induces exchange between the bound GDP and cellular GTP. Genetic studies have suggested that RCC1 may be involved in sensing the replication state of DNA and controlling the activation of Cdc2/cyclin B protein kinase through Ran.

-80°C

12352202