Phospho-NTRK1 (Tyr757) Antibody
CSB-PA271642
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
Overview
- SupplierCusabio
- Product NamePhospho-NTRK1 (Tyr757) Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Scientific DescriptionRequired for high-affinity binding to nerve growth factor (NGF), neurotrophin-3 and neurotrophin-4/5 but not brain-derived neurotrophic factor (BDNF). Known substrates for the Trk receptors are SHC1, PI 3-kinase, and PLC-gamma-1. Has a crucial role in the development and function of the nociceptive reception system as well as establishment of thermal regulation via sweating. Activates ERK1 by either SHC1- or PLC-gamma-1-dependent signaling pathway. Martin-Zanca D., Mol. Cell. Biol. 9:24-33(1989). Shelton D.L., J. Neurosci. 15:477-491(1995). The MGC Project Team, Genome Res. 14:2121-2127(2004).
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C
- UNSPSC12352203